Travins, Jeremy M.: search on Z-Library

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1

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations

Yen, Katharine, Travins, Jeremy, Wang, Fang, David, Muriel D., Artin, Erin, Straley, Kimberly, Padyana, Anil, Gross, Stefan, DeLaBarre, Byron, Tobin, Erica, Chen, Yue, Nagaraja, Raj, Choe, Sung, Jin,

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 1.22 MB

english, 2017

2

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1-Mutant Cancers

Popovici-Muller, Janeta, Lemieux, René M., Artin, Erin, Saunders, Jeffrey O., Salituro, Francesco G., Travins, Jeremy, Cianchetta, Giovanni, Cai, Zhenwei, Zhou, Ding, Cui, Dawei, Chen, Ping, Straley,

Journal:

ACS Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 429 KB

english, 2018

3

ChemInform Abstract: Rare Protein Turns: γ-Turn, Helix—Turn—Helix, and cis-Proline Mimics

Felicia A. Etzkorn, Jeremy M. Travins, Scott A. Hart

Journal:

Year:

2000

File:

PDF, 27 KB

2000

4

Design and Enantioselective Synthesis of a Peptidomimetic of the Turn in the Helix−Turn−Helix DNA-Binding Protein Motif

Travins, Jeremy M., Etzkorn, Felicia A.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 318 KB

english, 1997

5

Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists

John W. Ullrich, Robert Morris, Ronald C. Bernotas, Jeremy M. Travins, James Jetter, Rayomand Unwalla, Elaine Quinet, Ponnal Nambi, Irene Feingold, Christine Huselton, Christofer Enroth, Anna Wilhelms

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 512 KB

english, 2010

6

A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model

Wang, Fang, Travins, Jeremy, Lin, Zhizhong, Si, Yaguang, Chen, Yue, Powe, Josh, Murray, Stuart, Zhu, Dongwei, Artin, Erin, Gross, Stefan, Santiago, Stephanie, Steadman, Mya, Kernytsky, Andrew, Straley

Journal:

Journal of Inherited Metabolic Disease

Year:

2016

Language:

english

File:

PDF, 5.74 MB

english, 2016

7

Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

Nalin L. Subasinghe, Ehab Khalil, Jeremy M. Travins, Farah Ali, Shelley K. Ballentine, Heather R. Hufnagel, Wenxi Pan, Kristi Leonard, Roger F. Bone, Richard M. Soll, Carl S. Crysler, Nisha Ninan, Jen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

8

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation

Koivunen, Peppi, Lee, Sungwoo, Duncan, Christopher G., Lopez, Giselle, Lu, Gang, Ramkissoon, Shakti, Losman, Julie A., Joensuu, Päivi, Bergmann, Ulrich, Gross, Stefan, Travins, Jeremy, Weiss, Samuel,

Journal:

Year:

2012

Language:

english

File:

PDF, 922 KB

english, 2012

9

A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s

Nalin L. Subasinghe, Jeremy M. Travins, Farah Ali, Hui Huang, Shelley K. Ballentine, Juan José Marugán, Ehab Khalil, Heather R. Hufnagel, Roger F. Bone, Renee L. DesJarlais, Carl S. Crysler, Nisha Nin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

10

Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

Jeremy M. Travins, Farah Ali, Hui Huang, Shelley K. Ballentine, Ehab Khalil, Heather R. Hufnagel, Wenxi Pan, Joan Gushue, Kristi Leonard, Roger F. Bone, Richard M. Soll, Renee L. DesJarlais, Carl S. C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

11

Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo

Popovici-Muller, Janeta, Saunders, Jeffrey O., Salituro, Francesco G., Travins, Jeremy M., Yan, Shunqi, Zhao, Fang, Gross, Stefan, Dang, Lenny, Yen, Katharine E., Yang, Hua, Straley, Kimberly S., Jin,

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 982 KB

english, 2012

12

Aspartic Protease Inhibitors: Expedient Synthesis of 2-Substituted Statines

Travins, Jeremy M., Bursavich, Matthew G., Veber, Daniel F., Rich, Daniel H.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 64 KB

english, 2001

13

IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition

Kernytsky, Andrew, Wang, Fang, Hansen, Erica, Schalm, Stefanie, Straley, Kimberly, Gliser, Camelia, Yang, Hua, Travins, Jeremy, Murray, Stuart, Dorsch, Marion, Agresta, Sam, Schenkein, David P, Biller

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

14

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists

Jeremy M. Travins, Ronald C. Bernotas, David H. Kaufman, Elaine Quinet, Ponnal Nambi, Irene Feingold, Christine Huselton, Anna Wilhelmsson, Annika Goos-Nilsson, Jay Wrobel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 410 KB

english, 2010

15

Facile synthesis of d-amino acids from an l-serine-derived aziridine

Jeremy M. Travins, Felicia A. Etzkorn

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 248 KB

english, 1998

16

ChemInform Abstract: Facile Synthesis of D-Amino Acids from an L-Serine-Derived Aziridine.

Jeremy M. Travins, Felicia A. Etzkorn

Journal:

Year:

1999

File:

PDF, 28 KB

1999

17

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2 - and TET2 -Mutant Acute Myeloid Leukemia

Shih, Alan H., Meydan, Cem, Shank, Kaitlyn, Garrett-Bakelman, Francine E., Ward, Patrick S., Intlekofer, Andrew M., Nazir, Abbas, Stein, Eytan M., Knapp, Kristina, Glass, Jacob, Travins, Jeremy, Stral

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 5.17 MB

english, 2017

18

ChemInform Abstract: Aspartic Protease Inhibitors: Expedient Synthesis of 2-Substituted Statines.

Jeremy M. Travins, Matthew G. Bursavich, Daniel F. Veber, Daniel H. Rich

Journal:

Year:

2001

File:

PDF, 24 KB

2001

19

4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists

Ronald C. Bernotas, Robert R. Singhaus, David H. Kaufman, Jeremy M. Travins, John W. Ullrich, Rayomand Unwalla, Elaine Quinet, Mark Evans, Ponnal Nambi, Andrea Olland, Björn Kauppi, Anna Wilhelmsson,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 601 KB

english, 2010

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